The 17 Best Acne Spot Treatments to Zap Zits, Fast

Here's a fast-acting spot treatment that combines willow bark, sulfur, tea tree oil, azelaic acid, and more to fight breakouts and blemishes as you sleep. Its formula is also designed to stay put—even through tossing and turning—which means you don't have to worry about the paste staining your sheets or pillowcase.

One satisfied customer writes: "Oh my goodness, I have been using this pimple paste for the last few weeks and have truly noticed a difference in my skin, in love!!!" —Julianna M.

There's a reason over 31,000 shoppers are raving about this pink drying lotion from Mario Badescu: It combines acne-fighting ingredients like salicylic acid and sulfur to get rid of zits overnight.

One satisfied customer writes: "This stuff is great. No shaking. Dip the Q-Tip to the pink and dab. Sleep. Wash off in the morning. Watch your face look amazing." —Kay A.

A little goes a long way when it comes to this spot treatment. Mattifying clay is the star in Payot's top-rated formula, working to control excess oil while also reducing the size of breakouts. Plus, it's not only dermatologist-tested, but also non-comedogenic and paraben-free.

One satisfied customer writes: "I like the airy texture with green clay and tea tree scent! Also easy to remove in the morning." —Alex

When it comes to the acne spot treatment he most typically recommends to his clients, Hartman reaches for this popular option from La Roche-Posay. "I recommend La-Roche Posay Effaclar Duo Acne Treatment, which uses micronized benzoyl peroxide to penetrate deeper into the skin to clear active acne," he adds.

As a beauty enthusiast, I've tried my fair share of spot treatments over the years, but this one from Kinship is one I gravitate back to again and again. Not only does it work quickly to minimize pimples, but it also can be used on the entire face if you're dealing with a particularly bad breakout.

One satisfied customer writes: "I started using this a week ago and it really helps. It doesn’t dry my skin out, and reduces the look of a zit by the next day. I don’t feel a burn or anything when putting it on, but still does the job—it’s very gentle! Quickly absorbs too so you could apply makeup after, etc." —Elizabeth

This top-rated serum can be used as a spot treatment to minimize acne while improving the appearance of fine lines and hyperpigmentation at the same time.

One satisfied customer writes: "I recently added this to my SkinCeuticals routine and love it. I am 41, and have cystic acne on my chin and it has cleared up completely!" —Rebecca

The name of this popular treatment says it all: Not only is it powered by benzoyl peroxide to quickly fight breakouts, but it also uses ingredients like niacinamide, azelaic acid, and tea tree oil to soothe redness and irritation.

One satisfied customer writes: "I'm actually in awe of this product. I had some hormonal blemishes on my face and I used this product twice a day for two days. The pimples were raised, irritated and red at first, now three days later, they are essentially gone!! I'm seriously amazed. I've tried other acne spot treatments and none have ever worked this well." —Riley G.

For a set it and forget it option for acne, reach for these fun hydrocolloid patches from Starface. These stickers work overtime to shrink zits while protecting them from the elements. I love using them in my nighttime routine for ultimate beauty rest.

One satisfied customer writes: "They work great! I noticed a visible difference after using the Hydro-Stars. Also the packaging is super cute and convenient. Highly recommend!" —Jenn W.

Whether you decide to use this treatment in dabs or all over your face, your breakouts are no match for its powerful sulfur formula.

One satisfied customer writes: "I am completely obsessed with many of Sunday Riley’s products, and this is one of them. It's hands down the most effective spot blemish treatment I have used. I put a dab of the green cream on the blemish, leave it on over night, and within 24 hours it's significantly dried up. Decreases redness. The sulfur smell is not my favorite, but the product does the job." —shadowmoonbeam

We count Neutrogena's On-The-Spot Acne Spot Treatment as one of the OG pimple fighters. Its effective benzoyl peroxide formula absorbs quickly, and doesn't leave skin feeling dry once its applied.

One satisfied customer writes: "Pimples are visibly better after just one application. Got this for my teenager. He loves it too." —Tan X.

I previously tested SolaWave's Bye Acne: 3-Minute Pimple Spot Treatment, which combines blue and red light technology to minimize zits in a literal flash. It's an easy-to-use tool that's perfect for managing random acne flare-ups, whether you're at home or on the go.

One satisfied customer writes: "I’ve been using the device for a few weeks now and it is so good for getting rid of breakouts. It’s not a bad price for a light therapy device and it’s totally worth it!!" —Cait

This beloved gel uses a combination of two percent salicylic acid, retinol, and glycolic acid to fight acne, and also happens to work as an astringent to help control oil production.

One satisfied customer writes: "This product is the best when it comes to pimples. As soon as I get one, I put this on and it’s gone the next day. This product is excellent! And a must to have in your toiletries." —Sheriann

If you tend to develop whiteheads in addition to acne, this top-rated treatment gel from First Aid Beauty might be next up on your holy-grail skincare list. It uses two types of salicylic acid—two percent of the ingredient, along with its natural derivative, willow bark extract—to quickly clear your complexion.

One satisfied customer writes: "Works well! Helps cut break out time in half or better." —Felicia

Murad's hardworking spot treatment aims to minimize breakouts in four hours, and features a clear formula that won't stick out like a sore thumb under your foundation and concealer.

One satisfied customer writes: "This product is great. Applied at night and by morning, redness was gone. Blemishes reduced immensely. Highly recommend." —Shauna

This treatment uses a blend of succinic and salicylic acids plus sulfur powder to not only get rid of existing acne, but also helps prevent future breakouts from occurring. And since it also features hyaluronic acid, it'll leave your skin looking and feeling just a bit plumper.

One satisfied customer writes: "I will definitely buy this again, it really works. I put a small amount on bumps and blemishes before bed and they are definitely smaller in the morning. And they heal more quickly." —Franx

Here's a nighttime spot lotion from Renée Rouleau that works while you sleep to fight acne and whiteheads. As an added bonus, it can even be used to treat backne and chest breakouts.

One satisfied customer writes: "Best lotion to dry unwanted pimples I have ever used." –Carol E.

This treatment gel exclusively uses maximum strength salicylic acid to target unwanted breakouts, and also contains a wintergreen and rosebay willow complex that helps keep skin balanced.

One satisfied customer writes: "I’ve struggled with stress acne that pops up after a long hard day of work, and putting this on before bed wipes them out the next day without drying me out!" —Nikki M.